Next course “Genomics and Bioinformatics applied to Parasitology Research”, February 2023

News
  • 2022•10•19     Peru

    We are glad to announce the Course “Genomics and Bioinformatics applied to Parasitology Research”. This event is coordinated by Dr Ph. D Laura Kamenetsky, CONICET, Argentina, next February 13th to 28th 2023.

    Three Speakers from CONICET, Argentina will join the line-up of this course:

    Speakers

    • Guillermo Daniel Alonso, INGEBI-CONICET, Argentina
    • Marcela Cucher, CONICET, Argentina
    • Gisela Franchini, CONICET, Argentina

    The main objective of the course is that postgraduate students are internalized in new technologies applied to the study pathogens (virus, bacteria, fungus, protozoans, helminthes) by whole genome data. The course will focus on theoretical concepts of study of genomes and transcripts of organisms of different taxonomic groups and search of biomolecules of biotechnological interest. The theoretical information will be completed with specific practical studies of genomes and transcripts and the subsequent identification of candidates for diagnosis and control using molecular biology techniques developed jointly between research and clinical laboratories with a clear focus on technology transfer.

    Target audience

    Graduates or Master or Doctorates in careers related to life sciences (Biotechnology, Biology, Biochemistry, Genetics, Veterinary Medicine, Medicine and related careers). Other careers will be contemplated in the event that the postgraduate student has specialized in the subject matter (for example, Bachelor of Computer Science doing the Doctorate in Bioinformatics).

    Teorical

    1.Strategies for generating and analyzing x-omic data

    1.1. Generation of genome and transcriptome data: strategies currently available.

    1.2. Assembly and genome annotation: available tools and current limitations.

    1.3. Structural and functional characteristics of the genomes of different taxonomic groups.

    1.4. Data integration and information extraction of biotechnological application.

    1.5. Development and use of tools for the discovery of small RNAs from genomic data.

    1.6. Search and analysis of small RNAs as biomarkers in diseases.

     

    1. Identification of disease targets from x-omic data

    2.1. Infectious diseases

    2.1.1. Diagnosis and follow-up of infectious diseases: difficulties and challenges.

    2.1.2. miRNoma of parasitic platyhelminthes: expression throughout the development and possible biotechnological applications.

    2.1.3. Identification and characterization of antigens for use in the development of diagnostic methods of orphan helminthiasis.

    2.1.4. Immunoinformatics applied to the identification of diagnostic candidates.

    2.1.5. Discovery of new therapeutic targets in infectious diseases.

     

    Practical Activities

    Use of bioinformatics tools for genome assembly, analysis of transcriptomic data of both coding RNAs and specific tools for analysis and discovery of small non-coding RNAs. Use of specialized algorithms and databases for analysis and identification of therapeutic targets. Use of pathogen databases and strategies to extract information (EupathDB, WormBaseParasiteDB). Experimental validation of the bioinformatic predictions made by the detection of circulating microRNAs by RT-qPCR and integration of x-ionic data.

    The modalities of instruction will be lectures from 9am to 12 pm and practical from 13 pm to 17pm.

    The Open Call is to anyone interested. 

    Applicants must send intentional letter and CV to lauka@fbmc.fcen.uba.ar

    Deadline: December 15th, 2022

    You can download the information here